{"id":16728,"date":"2020-08-07T06:00:25","date_gmt":"2020-08-07T05:00:25","guid":{"rendered":"https:\/\/fight-malaria-blog.local\/?p=16728"},"modified":"2020-08-06T07:59:38","modified_gmt":"2020-08-06T06:59:38","slug":"new-plasmodium-transporter-channel-identified","status":"publish","type":"post","link":"https:\/\/fight-malaria-blog.local\/malaria-minute\/new-plasmodium-transporter-channel-identified\/","title":{"rendered":"New Plasmodium Transporter Channel Identified"},"content":{"rendered":"
The Latest Malaria News, in 60 Seconds.<\/strong><\/h5>

Scientists identify a new transporter channel in the parasitophorous vacuole, and researchers learn that LLINs in Papua New Guinea have not met the required bioefficacy standards since 2013.<\/p>\n

Malaria Minute on iTunes<\/a> and Spotify<\/a><\/p>

Transcript:<\/strong><\/h5>

Researchers have identified a new transporter channel in the parasitophorous vacuole, a structure produced by the malaria parasite to transfer proteins, lipids, nutrients, and metabolites from an infected red blood cell. The researchers detail two distinct channels: the parasitophorous vacuole membrane (PVM) and the parasitophorous plasma membrane (PPM) separated by the membrane contact site (MCS). The findings suggest that this configuration of the parasitophorous vacuole has evolved to separate hydrophilic and hydrophobic transport.<\/p>

Researchers have found that long-lasting insecticidal bed nets (LLINs), which were once effective in Papua New Guinea, have not met the required bioefficacy standards since 2013, correlating with a marked increase in malaria prevalence. Just 7% of nets manufactured after 2013 met the WHO requirement of 24hr mortality in lab testing, stressing the need for quality control.<\/p>

Sources:<\/strong><\/h5>

Contacting Domains Segregate a Lipid Transporter From a Solute Transporter in the Malarial Host\u2013Parasite Interface<\/a><\/p>

Decreased Bioefficacy of Long-Lasting Insecticidal Nets and the Resurgence of Malaria in Papua New Guinea <\/a><\/p>

<\/p>

Image Credits: <\/strong>‘The PV exhibits two structurally distinct regions’. Garten, M., Beck, J.R., Roth, R.\u00a0et al.<\/i> [Nat Commun<\/i>\u00a011,\u00a03825 (2020)<\/a>]<\/p>

Scientific Advisor:<\/strong> Elena G\u00f3mez-D\u00edaz, Institute of Parasitology and Biomedicine, Spain<\/p>","protected":false},"excerpt":{"rendered":"

Scientists identify a new transporter channel in the parasitophorous vacuole, and researchers learn that LLINs in Papua New Guinea have not met the required bioefficacy standards since 2013.<\/p>\n","protected":false},"author":1,"featured_media":16729,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false},"categories":[9],"tags":[],"yoast_head":"\nNew Plasmodium Transporter Channel Identified - The Fight Malaria Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/fight-malaria-blog.local\/malaria-minute\/new-plasmodium-transporter-channel-identified\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"New Plasmodium Transporter Channel Identified - The Fight Malaria Blog\" \/>\n<meta property=\"og:description\" content=\"Scientists identify a new transporter channel in the parasitophorous vacuole, and researchers learn that LLINs in Papua New Guinea have not met the required bioefficacy standards since 2013.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/fight-malaria-blog.local\/malaria-minute\/new-plasmodium-transporter-channel-identified\/\" \/>\n<meta property=\"og:site_name\" content=\"The Fight Malaria Blog\" \/>\n<meta property=\"article:published_time\" content=\"2020-08-07T05:00:25+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2020-08-06T06:59:38+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/fight-malaria-blog.local\/wp-content\/uploads\/2020\/08\/New-Plasmodium-Transporter-Channel-Identified.png\" \/>\n\t<meta property=\"og:image:width\" content=\"800\" \/>\n\t<meta property=\"og:image:height\" content=\"500\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Thomas Locke\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Thomas Locke\" \/>\n\t<meta name=\"twitter:label2\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/fight-malaria-blog.local\/malaria-minute\/new-plasmodium-transporter-channel-identified\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/fight-malaria-blog.local\/malaria-minute\/new-plasmodium-transporter-channel-identified\/\"},\"author\":{\"name\":\"Thomas Locke\",\"@id\":\"https:\/\/fight-malaria-blog.local\/#\/schema\/person\/866d37307e013f5a16202221b93ef75a\"},\"headline\":\"New Plasmodium Transporter Channel Identified\",\"datePublished\":\"2020-08-07T05:00:25+00:00\",\"dateModified\":\"2020-08-06T06:59:38+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/fight-malaria-blog.local\/malaria-minute\/new-plasmodium-transporter-channel-identified\/\"},\"wordCount\":256,\"publisher\":{\"@id\":\"https:\/\/fight-malaria-blog.local\/#organization\"},\"articleSection\":[\"Malaria Minute\"],\"inLanguage\":\"en-GB\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/fight-malaria-blog.local\/malaria-minute\/new-plasmodium-transporter-channel-identified\/\",\"url\":\"https:\/\/fight-malaria-blog.local\/malaria-minute\/new-plasmodium-transporter-channel-identified\/\",\"name\":\"New Plasmodium Transporter Channel Identified - The Fight Malaria Blog\",\"isPartOf\":{\"@id\":\"https:\/\/fight-malaria-blog.local\/#website\"},\"datePublished\":\"2020-08-07T05:00:25+00:00\",\"dateModified\":\"2020-08-06T06:59:38+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/fight-malaria-blog.local\/malaria-minute\/new-plasmodium-transporter-channel-identified\/#breadcrumb\"},\"inLanguage\":\"en-GB\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/fight-malaria-blog.local\/malaria-minute\/new-plasmodium-transporter-channel-identified\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/fight-malaria-blog.local\/malaria-minute\/new-plasmodium-transporter-channel-identified\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/fight-malaria-blog.local\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"New Plasmodium Transporter Channel Identified\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/fight-malaria-blog.local\/#website\",\"url\":\"https:\/\/fight-malaria-blog.local\/\",\"name\":\"The Fight Malaria Blog\",\"description\":\"Malaria News, Views and Interviews.\",\"publisher\":{\"@id\":\"https:\/\/fight-malaria-blog.local\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/fight-malaria-blog.local\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-GB\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/fight-malaria-blog.local\/#organization\",\"name\":\"Fight Malaria\",\"url\":\"https:\/\/fight-malaria-blog.local\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\/\/fight-malaria-blog.local\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/fight-malaria-blog.local\/wp-content\/uploads\/2020\/07\/blog_logo-20200728-212450.svg\",\"contentUrl\":\"https:\/\/fight-malaria-blog.local\/wp-content\/uploads\/2020\/07\/blog_logo-20200728-212450.svg\",\"caption\":\"Fight Malaria\"},\"image\":{\"@id\":\"https:\/\/fight-malaria-blog.local\/#\/schema\/logo\/image\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\/\/fight-malaria-blog.local\/#\/schema\/person\/866d37307e013f5a16202221b93ef75a\",\"name\":\"Thomas Locke\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\/\/fight-malaria-blog.local\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/4e07b1fc2fb741436038290480c02087?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/4e07b1fc2fb741436038290480c02087?s=96&d=mm&r=g\",\"caption\":\"Thomas Locke\"},\"url\":\"https:\/\/fight-malaria-blog.local\/author\/fightmalaria\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"New Plasmodium Transporter Channel Identified - The Fight Malaria Blog","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/fight-malaria-blog.local\/malaria-minute\/new-plasmodium-transporter-channel-identified\/","og_locale":"en_GB","og_type":"article","og_title":"New Plasmodium Transporter Channel Identified - The Fight Malaria Blog","og_description":"Scientists identify a new transporter channel in the parasitophorous vacuole, and researchers learn that LLINs in Papua New Guinea have not met the required bioefficacy standards since 2013.","og_url":"https:\/\/fight-malaria-blog.local\/malaria-minute\/new-plasmodium-transporter-channel-identified\/","og_site_name":"The Fight Malaria Blog","article_published_time":"2020-08-07T05:00:25+00:00","article_modified_time":"2020-08-06T06:59:38+00:00","og_image":[{"width":800,"height":500,"url":"https:\/\/fight-malaria-blog.local\/wp-content\/uploads\/2020\/08\/New-Plasmodium-Transporter-Channel-Identified.png","type":"image\/png"}],"author":"Thomas Locke","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Thomas Locke","Estimated reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/fight-malaria-blog.local\/malaria-minute\/new-plasmodium-transporter-channel-identified\/#article","isPartOf":{"@id":"https:\/\/fight-malaria-blog.local\/malaria-minute\/new-plasmodium-transporter-channel-identified\/"},"author":{"name":"Thomas Locke","@id":"https:\/\/fight-malaria-blog.local\/#\/schema\/person\/866d37307e013f5a16202221b93ef75a"},"headline":"New Plasmodium Transporter Channel Identified","datePublished":"2020-08-07T05:00:25+00:00","dateModified":"2020-08-06T06:59:38+00:00","mainEntityOfPage":{"@id":"https:\/\/fight-malaria-blog.local\/malaria-minute\/new-plasmodium-transporter-channel-identified\/"},"wordCount":256,"publisher":{"@id":"https:\/\/fight-malaria-blog.local\/#organization"},"articleSection":["Malaria Minute"],"inLanguage":"en-GB"},{"@type":"WebPage","@id":"https:\/\/fight-malaria-blog.local\/malaria-minute\/new-plasmodium-transporter-channel-identified\/","url":"https:\/\/fight-malaria-blog.local\/malaria-minute\/new-plasmodium-transporter-channel-identified\/","name":"New Plasmodium Transporter Channel Identified - The Fight Malaria Blog","isPartOf":{"@id":"https:\/\/fight-malaria-blog.local\/#website"},"datePublished":"2020-08-07T05:00:25+00:00","dateModified":"2020-08-06T06:59:38+00:00","breadcrumb":{"@id":"https:\/\/fight-malaria-blog.local\/malaria-minute\/new-plasmodium-transporter-channel-identified\/#breadcrumb"},"inLanguage":"en-GB","potentialAction":[{"@type":"ReadAction","target":["https:\/\/fight-malaria-blog.local\/malaria-minute\/new-plasmodium-transporter-channel-identified\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/fight-malaria-blog.local\/malaria-minute\/new-plasmodium-transporter-channel-identified\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/fight-malaria-blog.local\/"},{"@type":"ListItem","position":2,"name":"New Plasmodium Transporter Channel Identified"}]},{"@type":"WebSite","@id":"https:\/\/fight-malaria-blog.local\/#website","url":"https:\/\/fight-malaria-blog.local\/","name":"The Fight Malaria Blog","description":"Malaria News, Views and Interviews.","publisher":{"@id":"https:\/\/fight-malaria-blog.local\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/fight-malaria-blog.local\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-GB"},{"@type":"Organization","@id":"https:\/\/fight-malaria-blog.local\/#organization","name":"Fight Malaria","url":"https:\/\/fight-malaria-blog.local\/","logo":{"@type":"ImageObject","inLanguage":"en-GB","@id":"https:\/\/fight-malaria-blog.local\/#\/schema\/logo\/image\/","url":"https:\/\/fight-malaria-blog.local\/wp-content\/uploads\/2020\/07\/blog_logo-20200728-212450.svg","contentUrl":"https:\/\/fight-malaria-blog.local\/wp-content\/uploads\/2020\/07\/blog_logo-20200728-212450.svg","caption":"Fight Malaria"},"image":{"@id":"https:\/\/fight-malaria-blog.local\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/fight-malaria-blog.local\/#\/schema\/person\/866d37307e013f5a16202221b93ef75a","name":"Thomas Locke","image":{"@type":"ImageObject","inLanguage":"en-GB","@id":"https:\/\/fight-malaria-blog.local\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/4e07b1fc2fb741436038290480c02087?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/4e07b1fc2fb741436038290480c02087?s=96&d=mm&r=g","caption":"Thomas Locke"},"url":"https:\/\/fight-malaria-blog.local\/author\/fightmalaria\/"}]}},"_links":{"self":[{"href":"https:\/\/fight-malaria-blog.local\/wp-json\/wp\/v2\/posts\/16728"}],"collection":[{"href":"https:\/\/fight-malaria-blog.local\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/fight-malaria-blog.local\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/fight-malaria-blog.local\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/fight-malaria-blog.local\/wp-json\/wp\/v2\/comments?post=16728"}],"version-history":[{"count":0,"href":"https:\/\/fight-malaria-blog.local\/wp-json\/wp\/v2\/posts\/16728\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/fight-malaria-blog.local\/wp-json\/wp\/v2\/media\/16729"}],"wp:attachment":[{"href":"https:\/\/fight-malaria-blog.local\/wp-json\/wp\/v2\/media?parent=16728"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/fight-malaria-blog.local\/wp-json\/wp\/v2\/categories?post=16728"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/fight-malaria-blog.local\/wp-json\/wp\/v2\/tags?post=16728"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}