{"id":16756,"date":"2020-09-04T06:00:49","date_gmt":"2020-09-04T05:00:49","guid":{"rendered":"https:\/\/fight-malaria-blog.local\/?p=16756"},"modified":"2020-09-02T21:06:14","modified_gmt":"2020-09-02T20:06:14","slug":"researchers-produce-cell-atlas-of-mosquito-immune-system","status":"publish","type":"post","link":"https:\/\/fight-malaria-blog.local\/malaria-minute\/researchers-produce-cell-atlas-of-mosquito-immune-system\/","title":{"rendered":"Researchers Produce Cell Atlas of Mosquito Immune System"},"content":{"rendered":"
The Latest Malaria News, in 60 Seconds.<\/strong><\/h5>

Researchers produce a \u2018cell atlas\u2019 of the mosquito immune system, and new hydrological prediction models identify a more complex pattern of malaria suitability.<\/p>\n

Malaria Minute on iTunes<\/a> and Spotify<\/a><\/p>


Transcript:<\/strong><\/h5>

Researchers have produced a \u2018cell atlas\u2019 of the mosquito immune system using single-cell sequencing. This more granular understanding of how the mosquito fights infection at the cellular level is key to developing new therapies against malaria. One potential approach involves \u2018immune priming\u2019; stimulating immune cells to develop adaptive immunity and protection for future infection. The researchers in this study identified that a particular cell, the megacyte, is involved in this process.<\/p>

Malaria transmission is dependent on both air temperature and the availability of stagnant water, and both are dependent on climate change. By using models that consider water movement and usage – not just the amount of water falling from the sky – researchers have identified a more complex pattern of malaria suitability. This new type of hydrological model demonstrates different transmission patterns depending on the local geography.<\/p>

Sources:<\/strong><\/h5>

Mosquito Cellular Immunity at Single-Cell Resolution<\/a><\/p>

Incorporating Hydrology Into Climate Suitability Models Changes Projections of Malaria Transmission in Africa<\/a><\/p>

<\/p>


Image Credits:\u00a0<\/strong>CDC\/ James Gathany [18754<\/a>]<\/p>

Scientific Advisor:<\/strong> Elena G\u00f3mez-D\u00edaz, Institute of Parasitology and Biomedicine, Spain<\/p>","protected":false},"excerpt":{"rendered":"

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