{"id":16773,"date":"2020-09-25T06:00:21","date_gmt":"2020-09-25T05:00:21","guid":{"rendered":"https:\/\/fight-malaria-blog.local\/?p=16773"},"modified":"2020-09-23T21:00:56","modified_gmt":"2020-09-23T20:00:56","slug":"surface-tension-key-to-dantu-blood-group-protection","status":"publish","type":"post","link":"https:\/\/fight-malaria-blog.local\/malaria-minute\/surface-tension-key-to-dantu-blood-group-protection\/","title":{"rendered":"Surface Tension Key to Dantu Blood Group Protection"},"content":{"rendered":"
The Latest Malaria News, in 60 Seconds.<\/strong><\/h5>\r\n

The secrets to the Dantu blood group\u2019s innate protection from malaria are revealed, researchers identify the protein needed for efficiency egress of rodent malaria from the liver, and a letter Trends in Parasitology defends the mosquito.<\/p>\r\n\n

Malaria Minute on iTunes<\/a> and Spotify<\/a><\/p>\r\n

\r\n
Transcript:<\/strong><\/h5>\r\n

Individuals with a rare blood variant found only in parts of East Africa, named Dantu blood type, have long been known to have innate protection from malaria. Yet the cause of this protection has never been fully understood. By following the process of invasion using video microscopy, researchers have now found that higher-than-average surface tension of Dantu red blood cells block malaria parasite entry and therefore protect against the most severe form of the disease.<\/p>\r\n

Researchers have found that a specific protein – Pb<\/em>SERA4<\/span>\u00a0– is required for efficient egress of the rodent malaria parasite P. berghei<\/em> from the liver. When removed, the ability of the malaria parasite to establish blood-stage infection, whilst not eliminated, is strongly inhibited.<\/p>\r\n

The mosquito is often referred to as the \u2018world\u2019s deadliest killer\u2019; a new letter in the Trends in Parasitology emphasises the mosquito\u2019s role as a vector of disease, not as a killer in and of itself.<\/p>\r\n

Sources:<\/strong><\/h5>\r\n

Red Blood Cell Tension Protects Against Severe Malaria in the Dantu Blood Group<\/a><\/p>\r\n

A Plasmodium<\/em> Cysteine Protease Required for Efficient Transition From the Liver Infection Stage<\/a><\/p>\r\n

In Fairness to Mosquitoes<\/a><\/p>\r\n

<\/p>\r\n

\r\n

Image Credits:<\/strong> NIAID [Flickr<\/a>]<\/span><\/p>\r\n

<\/p>\r\n

Scientific Advisor:<\/strong> Elena G\u00f3mez-D\u00edaz, Institute of Parasitology and Biomedicine, Spain<\/span><\/p>","protected":false},"excerpt":{"rendered":"

The secrets to the Dantu blood group\u2019s innate protection from malaria are revealed, researchers identify the protein needed for efficiency egress of rodent malaria from the liver, and a letter Trends in Parasitology defends the mosquito.<\/p>\n","protected":false},"author":1,"featured_media":16774,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false},"categories":[9],"tags":[],"yoast_head":"\nSurface Tension Key to Dantu Blood Group Protection - The Fight Malaria Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/fight-malaria-blog.local\/malaria-minute\/surface-tension-key-to-dantu-blood-group-protection\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Surface Tension Key to Dantu Blood Group Protection - 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