{"id":16778,"date":"2020-10-02T06:00:51","date_gmt":"2020-10-02T05:00:51","guid":{"rendered":"https:\/\/fight-malaria-blog.local\/?p=16778"},"modified":"2020-09-30T22:17:32","modified_gmt":"2020-09-30T21:17:32","slug":"crispr-based-malaria-test-useful-for-low-resource-settings","status":"publish","type":"post","link":"https:\/\/fight-malaria-blog.local\/malaria-minute\/crispr-based-malaria-test-useful-for-low-resource-settings\/","title":{"rendered":"CRISPR-Based Malaria Test Useful for Low-Resource Settings"},"content":{"rendered":"
The Latest Malaria News, in 60 Seconds.<\/strong><\/h5>\r\n

A new malaria test offers high specificity from a small form factor, and researchers develop an imaging tool to examine mosquito feeding behaviour.<\/p>\r\n\n

Malaria Minute on iTunes<\/a> and Spotify<\/a><\/p>\r\n


\r\n
Transcript:<\/strong><\/h5>\r\n

The current tools for diagnosing malaria have limitations; rapid diagnostic tests lack sensitivity and specificity whilst PCR-based molecular tests require time and labour. A new CRISPR-based diagnostic approach, using the \u2018SHERLOCK\u2019 protocol, seeks to bridge the gap between the two, offering accurate results from a small form factor. It delivers results in 60 minutes and can differentiate between multiple strains of P. falciparum<\/em> and P. ovale<\/em> malaria with 100% specificity. This new generation of tests has particular application to low-resource settings where they will be useful to detect malaria prevalence among asymptomatic patients.<\/p>\r\n

By deploying high-resolution imaging, researchers are now one step closer to understanding the complex feeding behaviour of mosquitoes. The so-called \u2018biteOscope\u2019 is a device that attracts mosquitoes to a host mimic with artificial blood. The host is transparent to allow for the recording of activity, with a particular focus on movement and posture.<\/p>\r\n

Sources:<\/strong><\/h5>\r\n

Ultrasensitive CRISPR-Based Diagnostic for Field-Applicable Detection of Plasmodium<\/em> Species in Symptomatic and Asymptomatic Malaria<\/a><\/p>\r\n

BiteOscope, an Open Platform to Study Mosquito Biting Behavior<\/a><\/p>\r\n

<\/p>\r\n


\r\n

Image Credits:<\/strong> Experiment Test [Needpix<\/a>]<\/p>\r\n

<\/p>\r\n

Scientific Advisor:<\/strong> Elena G\u00f3mez-D\u00edaz, Institute of Parasitology and Biomedicine, Spain<\/span><\/p>","protected":false},"excerpt":{"rendered":"

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