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Thomas Locke

Malaria Minute

How Drug Resistance Is Impacting Malaria Elimination

Researchers detail the extent of antimalarial drug resistance around the world, considering its implications for the WHO’s Global Technical Strategy for Malaria.

By Thomas Locke, 2 days2 days ago
Malaria Minute

New Insights Into the Biophysical Characteristics of RTS,S Antibodies

Researchers reveal the importance of antibody affinity and dissociation constant in parasite neutralisation.

By Thomas Locke, 2 months1 week ago
Malaria Minute

Researchers Use AI to Identify Morphologically Similar Mosquitoes

Researchers develop an image recognition tool to identify mosquitoes in the field, and a new paper highlights the nuanced realities of malaria decision-making in endemic regions.

By Thomas Locke, 4 months4 months ago
Malaria Minute

Shedding Enzyme Essential for Parasite Survival

Researchers find that SUB2, a malaria parasite enzyme, helps the parasite survive in the human host and new research characterises cerebral malaria infection in adults and children.

By Thomas Locke, 4 months4 months ago
Malaria Minute

Parasite Biomarkers Predict Transmission Potential

Researchers identify three biomarkers associated with gametocytes development that predict transmission potential, and the use of LAMP-based malaria diagnostic tools is evaluated.

By Thomas Locke, 4 months4 months ago
Malaria Minute

WHO Publish Annual World Malaria Report

The WHO publishes its annual World Malaria Report and a new article stresses the need for highly-effective vaccines to eliminate malaria.

By Thomas Locke, 4 months4 months ago
Malaria Minute

Conserved Antigen Pb22 Plays a Critical Role in Male Gametogenesis in P. Berghei

Pb22, a protein expressed by Plasmodium berghei, may play an important role in the transmission of malaria, and review on the use of tafenoquine finds that the drug is well-tolerated and effective.

By Thomas Locke, 4 months5 months ago
Malaria Minute

Parasite Viability Is a Superior Indicator of Antimalarial Drug Activity

Determining drug efficacy through parasite clearance half-life may underestimate the activity of some antimalarial drugs, and the WHO publishes new guidance on the use of genetically modified mosquitoes.

By Thomas Locke, 5 months5 months ago
Malaria Minute

‘Memory-Like’ Imprints in γδ T Cells Allow for Better Response to Future Malaria Infection

New research examines the long-term impact of malaria infection on γδ T cells, and a review of malaria cases among pregnant women in Lagos, Nigeria, explores the impact of preventative measures on the prevalence of malaria and anaemia.

By Thomas Locke, 5 months5 months ago
Malaria Minute

Microneedle Patches the Future of Malaria Diagnosis

A new diagnostic tool using microneedles eliminates the need for a fingerprick, and researchers develop a more efficient gene-drive system that overcomes the challenge of genetic resistance.

By Thomas Locke, 5 months5 months ago

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We assimilate malaria research and communicate key findings in podcast form.

Along the way, we interview scientists and decision-makers from around the world.

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Distilling the science of malaria

We assimilate malaria research and communicate key findings in podcast form.

Along the way, we interview scientists and decision-makers from around the world.

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