At Fight Malaria, our team focuses on producing and distributing educational resources in order to prevent malaria. However, there are of course lots of other methods and techniques developed with a unifying aim to make scientific advancements in the prevention and elimination of fatal diseases such as malaria.

If you are reading this, you are probably aware that education, mosquito nets, repellents and aromatherapy are ways to prevent malaria. However, there are other routes:

The Pathogen Box

To put it simply, the Pathogen Box is a scientific kit containing 400 different drug-like molecules with the potential to fight a diverse range of neglected tropical diseases, such as malaria. The box was brought forward by Medicines for Malaria Venture (MMV), a Geneva-based nonprofit organization that discovers and develops antimalarial medicines.

Now for the more scientific side! The compounds are distributed in 96-well plates containing 10​μL of a 10mM dimethyl sulfoxide (DMSO) solution of each compound.

The Pathogen Box contains compounds active against:

If you are a keen scientist or researcher with a passion for fighting disease, then the Pathogen Box might be for you! Just request one from the official website and you will receive 400 molecules to help catalyse neglected disease drug discovery. In return, researchers are asked to share any discoveries and scientific data in the public domain within two years. This creates a collaborative, effective forum in which research on disease can be shared. MMV scientists can also provide scientific advice on any screening hits and also supply additional quantities of compounds for follow-up studies.

Without research and sharing information, diseases such as malaria will not be prevented as effectively and will cause greater significant damage to people’s lives, health and communities. It is essential to find out more about these diseases, and share data in order to prevent and eradicate them. Fatal or life-changing diseases such as malaria can be prevented, and through the distribution of accurate and high-quality educational material, extensive scientific research and effective sharing of information, progress will be made!

But, what if you are not a dedicated researcher or scientist; how can you help? Well, there are plenty of ways to help just in our network alone. By writing insightful blog posts, sharing our resources and spreading the word, you can make an impact!

If you are a malaria researcher, blogger or scientist and would like to submit an article for our blog, we’d love to hear from you! Email any articles you wish to share to: [email protected]

You can find out more about the Pathogen Box here

Thanks to the Medicines for Malaria Venture (MMV) for granting Fight Malaria permission to publish this article and to reproduce their photographs.

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Categories: Fight Malaria